Method name: praziquantel tablets – praziquantel – High Performance Liquid Chromatography
Applications: The method for determining the content of praziquantel praziquantel tablets using high performance liquid chromatography.
This method is applicable to praziquantel tablets.
Method: the small study sample, internal standard solution dissolved in methanol and then diluted into the HPLC chromatography with UV absorbance detector at a wavelength of 263nm peak area detected praziquantel, calculated its content.
Reagents: 1 methanol
2. Α-asarone
Equipment: 1 Instrument
1.1 HPLC
1.2 column
Octadecylsilane bonded silica as a filler
1.3 UV absorption detector
2 chromatographic conditions
2.1 mobile phase: methanol-water = 10040
2.2 detection wavelength: 263nm
2.3 column temperature: room temperature
Preparation of internal standard solution 1: Sample Preparation.
Precision Weigh α-asarone amount, dissolved in methanol and diluted into each 1mL solution containing 0.4mg, namely the internal standard solution.
Preparation of 2 reference solution
Precision Weigh praziquantel reference about 100mg, set 10mL volumetric flask, precision internal standard solution 5mL, and shake to dissolve, diluted with methanol to the mark, shake, is the reference solution.
Preparation of the test solution 3.
20 to take the test, accurately weighed, small study, accurately weighed amount (approximately equivalent to praziquantel 100mg), set 10mL volumetric flask, precision internal standard solution 5mL, and shake to dissolve, dilute with methanol to scale, shake, that is, the test solution.
Note: “Precision Weigh” means to check the weight should be accurately referred to take the weight of one-thousandth. ‘Precise amount “means the amount of the volume should meet the accuracy requirements of national standards for the volume pipettes.
Steps: precision drawing reference solution and the test solution 10mL, high performance liquid chromatography with UV absorbance detector praziquantel (C19H24N2O2) at a wavelength of 263nm peak area, calculates its content.
Category Archives: Intermediate
povidone iodine information
povidone iodine
Formula (Formula): C6H9I2NO
Molecular Weight (Molecular Weight): 364.95
CAS No:. 25655-41-8
Quality Index (Specification)
Appearance (Appearance): reddish brown or yellow-brown amorphous powder
Content (Purity): a variety of molecular weights
Physical and chemical properties (Physical Properties)
Solubility: PVP is a water-soluble polymer, both miscible with water and can dissolve many alcohols, carboxylic acids, amines, halogenated hydrocarbons and other organic solvents.
Film forming: PVP having very good film-forming properties, PVP was dissolved in certain solvents such as water, methanol, ethanol and the like may be cast or coated film.
Water absorption: PVP with a strong water absorption and moisture retention, commonly used in advanced cosmetics.
Increase in dispersibility and solubility: PVP small molecules have a good dispersion, to prevent mutual aggregation of particles and precipitation. PVP can increase the number of substances
Solubility in aqueous solution.
Complexation: O atoms in the molecule PVP, N atoms are typical ligand atom, it has the ability to complex with some substances, such as iodine, benzene
Class A morpholino and a variety of sulfa drugs.
Effective Iodine 9.0 – 12.0%, an iodine ion% max: 6.6, Heavy metals ppm max: 20, Ash% max: 0.1, nitrogen content% :9.5-11 .5, pH value (10% solution) 1.5 to 5.0 Loss on drying % max: 8.0.
Use (Useage)
Cosmetic
PVP excellent surface activity, film, no skin irritation, no allergic reactions and other characteristics of household chemicals, especially in cosmetics,
Application of skin care products, hair care products and cleaning supplies, etc. has broad prospects. If added with PVP of hairspray and mousse persistent stereotypes,
Has good gloss, and because of PVP with some absorbent, smooth and moisturize the hair will not look boring. Plus a PVP
Skin care products, not only a good moisturizing effect, and in the film formed on the surface of the skin to make the skin with the outside world (such as sunlight) separated, played Paul
Protect the skin.
Medicine
PVP good solubility, Increase soluble, physiologically compatible, bonding capacity and complexing ability of other properties, in the field of medicine and medical health,
Is widely used, can be used as binders, excipients, coating agents, disintegrants, solubilizers, disinfectant, solubilizers, release agent,
Capsule shell, a dispersion stabilizer, film and the like.
Industrial Applications
Adhesives: PVP has a very good solution viscosity, solid glue stick, stamp, band-aid, plaster bandages used as adhesives.
Paints and inks: PVP having excellent dispersibility, the PVP added to the coating to increase the viscosity, improve the coloring power, eliminating
Floating color phenomenon, pigment dispersion and stabilization of the composition, improved gloss, avoid flocculation of the pigment.
The new membrane materials: PVP not only can improve the hydrophilicity of the film, but also by selecting different molecular weight and the amount of PVP
Control, to control the pore size and distribution. Also PVP in drag reduction materials, glass fiber, laser disc, light curing resin, photosensitive materials have applications in areas such as new materials.
copper 8-hydroxyquinoline information
Basic Information
[Chinese name] hydroxyquinoline copper; 8 – hydroxyquinoline copper
[Chinese alias] bis (8 – hydroxy-quinolyl) copper
[English name] oxine-copper; copper 8-hydroxyquinoline
[English Name] Bis (8-hydroxyquinolinato) copper (II); Copper (II) Bis (8-hydroxyquinolinate); Oxine-Copper
[CAS No. 10380-28-6]
[MF] C18H12N2O2Cu
【Molecular Weight】 351.84
[Purity] ≥ 98%
[MDL No.】 MFCD00067392
2 Characters
Yellow-green crystalline powder, odorless, tasteless, non-volatile, no deliquescence, flame retardant, black decompose at higher temperatures, insoluble in water and most organic solvents, slightly soluble in quinoline, pyridine, glacial acetic acid, chloroform, weak , soluble in acid, alkali case decomposition.
Industrial green or brown solid. The nature of the general stable, but decompose at high temperatures deterioration.
Three physical parameters
Solubility: 20 times fully dissolved in glacial acetic acid
4 Quality Specifications
Purity: ≥ 98%
Loss on drying: ≤ 0.5%
Hydrochloride: ≤ 0.01%
Sulfate: ≤ 0.1%
5 Instructions for use
Mildew; pesticides, pharmaceuticals synthesis of metal corrosion inhibitor;
Used as a fungicide in agriculture. Also used as rope, wire, leather, vinyl mildew.
By 8 – hydroxyquinoline sulfate derived role.
6 Storage Transportation
Dark dry and ventilated place
UN number: UN3077
Clotrimazole MSDS
Basic Information
Chinese Name
Clotrimazole
Chinese alias
Antifungal the 1st ; triphenyl imidazole chloroformate ; chlorobenzene imidazole ; kill ringworm net ; 1 – ((2 – chlorophenyl ) diphenylmethyl )-1H- imidazol-
Name
clotrimazole crystalline
English Name
Clotrimazole ZnSO4 complex; 1 [(2-chlorophenyl) diphenylmethyl]-1H-imidazole; Clotrimazole
2CAS :23593-75-1
EINECS :245-764-8 Formula : C22H17ClN2 MW: 344.8368
3 physical and chemical properties
Appearance: white powder or colorless crystalline powder. Melting point 147-149 ℃. Relative density : 1.13g/cm3. Solubility : Soluble in ethanol , acetone , chloroform, insoluble in water . Odorless, tasteless , rapid decomposition in acid solution .
Clotrimazole hydrochloride, m.p. 159 ℃.
4 Use
Anti- fungal drugs [ 1 ] , for the treatment of skin and deep fungal infections
Raw materials
Benzene , acetone , toluene , o- chlorobenzoyl chloride , o- chloro- benzotrichloride , thionyl chloride, imidazole, aluminum trichloride, petroleum ether
Clotrimazole
A broad-spectrum anti-fungal effect . Some superficial and deep fungal fungi have antibacterial activity . The main clinical for topical treatment of skin mycosis , such as hand, foot and ringworm , tinea , ear , vaginal mycosis . This product is toxic, orally gastrointestinal reactions , abnormal liver function , and leukopenia . Has been seldom used . Topical no adverse reactions , sometimes local inflammation . Topical 1% to 3% cream ; suppositories.
Copper 8-hydroxyquinoline MSDS
1 Basic information
[ Chinese name] hydroxyquinoline copper ; 8 – hydroxyquinoline copper
Alias [ Chinese ] bis (8 – hydroxy- quinolyl ) copper
[English name] oxine-copper; copper 8-hydroxyquinoline
[ English Name ] Bis (8-hydroxyquinolinato) copper (II); Copper (II) Bis (8-hydroxyquinolinate); Oxine-Copper
[ CAS No. 10380-28-6 ]
[ MF ] C18H12N2O2Cu
【 Molecular Weight 】 351.84
[ Purity ] ≥ 98%
[ MDL No. 】 MFCD00067392
2 Characters
Yellow-green crystalline powder , odorless , tasteless , non-volatile, no deliquescence , flame retardant, black decompose at higher temperatures , insoluble in water and most organic solvents , slightly soluble in quinoline , pyridine, glacial acetic acid , chloroform , weak , soluble in acid, alkali case decomposition.
Industrial green or brown solid. The nature of the general stable, but decompose at high temperatures deterioration .
Three physical parameters
Solubility: 20 times fully dissolved in glacial acetic acid
4 Quality Specifications
Purity : ≥ 98%
Loss on drying : ≤ 0.5%
Hydrochloride : ≤ 0.01%
Sulfate : ≤ 0.1%
5 Instructions for use
Mildew ; pesticides, pharmaceuticals synthesis of metal corrosion inhibitor ;
Used as a fungicide in agriculture . Also used as rope, wire , leather, vinyl mildew .
By 8 – hydroxyquinoline sulfate derived role .
6 Storage Transportation
Dark dry and ventilated place
UN number : UN3077
8-Hydroxyquinoline MSDS
1 Basic information
Chinese Name: 8 – hydroxyquinoline
Chinese alias: 8 – quinoline hydroxide 8 – hydroxy naphthalene nitrogen, ortho hydroxy nitrogen (Miscellaneous) naphthalene, oxine , 8 – hydroxy-naphthyridine
Name :8-Hydroxyquinoline
English Name :8-Hydroxyquinoline; 8-Oxychinolin; 8-Quinolinol; Oxine
Grade: AR
CAS Number :148 -24-3
Formula: C9H7NO
Molecular Weight: 145.16
CAS Number :148 -24-3
No. MDL: MFCD00006807
EINECS No. :205 -711-1
RTECS Number: VC4200000
BRN No.: 114512
PubChem number: 24855220
2 Characters
White or light yellow crystal or crystalline powder , insoluble in water and ether , soluble in ethanol , acetone, chloroform , benzene or dilute acid, can be sublimated. Less corrosive. Low toxicity, LD504800mg/kg.
3 Quality Standards
|
Name (content and impurity content%) |
Index |
Result |
|
8 – hydroxy quinoline (C9H7NO) content ≥ |
99.5 |
99.7 |
|
Melting point ℃ |
73.0 ~ 74.5 (1 ℃) |
73.1 ~ 74.0 (1 ℃) |
|
Sensitivity tests for magnesium |
Qualified |
Qualified |
|
Acid dissolution test |
Qualified |
Qualified |
|
Residue on ignition (as sulfate) ≤ |
0.02 |
0.015 |
|
Chloride (Cl) ≤ |
0.002 |
0.0015 |
|
Sulfate (SO4) |
0.01 |
0.006 |
4 Physical Parameters
[1]
Melting point (º C): 75 ~ 76
Boiling Point (º C): 267
Density: 1.03
5 Quality Specifications
Purity: ≥ 99%
Melting point ≥ 75 ℃
Residue on ignition (as sulfate): ≤ 0.02%
Chloride : ≤ 0.002%
Sulfate: ≤ 0.01%
Magnesium sensitivity test: pass
Acid dissolution test: pass
6 dissolved
Soluble in ethanol , acetone, chloroform , benzene, and a mineral acid, almost insoluble in water .
8 – hydroxy quinoline is bisexual, soluble in strong acid , alkali, alkali ions in ionization, can be combined in acid hydrogen ions in PH = 7时solubility minimum.
7 toxicological data
1 Acute toxicity: rat oral LD50: 1200 mg / kg; mouse oral LC50: 20 gm / kg;
Intraperitoneal LD rat: 43 gm / kg; mouse subcutaneous LCLo: 83600 ug / kg.
2 inhalation toxicity: rat:> 1210 mg/m3/6H
The substance may be hazardous to the environment, the water should be given special attention.
8 molecular structure data
1, the molar refractive index: 44.06
2, molar volume (m3/mol): 115.2
3, parachor (90.2K): 320.2
4, the surface tension (dyne / cm): 59.7
5, the polarization rate (10-24cm3): 17.47
9 computational chemistry data
A hydrophobic parameter calculation reference value (XlogP): 2
2, the number of hydrogen bonds for the body: 1
3, the number of hydrogen bond acceptors: 2
4, rotatable bond: 0
5, topological molecular polar surface area (TPSA): 33.1
6, the number of heavy atoms: 11
7, the surface charge: 0
8, the complexity: 138
9, the number of atomic isotopes: 0
10, determines the number of atoms stereocenter: 0
11, the number of uncertain atom stereocenter: 0
12, determines the number of bond stereocenter: 0
13, the number of uncertain bond stereocenter: 0
14, the number of covalent bond unit: 1
10 synthetic
1 o-aminophenol by cyclization reaction. Glycerol was added to the acid reaction pot, stirring slowly adding concentrated sulfuric acid, while the o-aminophenol , o-nitrophenol were added sequentially, fuming sulfuric acid to join the 65% of the total. Heating up to 125 ℃, heating was stopped and warm naturally to 140 ℃, when the temperature was returned to 136 ℃. The rest continues oleum added maintaining the temperature at 137 ℃. After the addition of acid, heat 4h, cooling to 100 ℃, 10 times the amount of pumped water bloom (in o-phenol) acid pot was stirred and heated to 75-80 ℃, with 30% sodium hydroxide solution to a pH of 7-7.2. The precipitate was discharged hot, cooling blocks, sublimation under reduced pressure, to give 8 – hydroxyquinoline products.
2 o-aminophenol, o-nitrophenol, glycerol , acetic acid mixture of concentrated sulfuric acid was added, and the mixture was heated to boiling until the beginning. And then refluxed on an oil bath to remove unreacted nitrophenol by steam distillation. Cooled, neutralized with sodium hydroxide solution and recovered by steam distillation, i.e., to give 8 – hydroxyquinoline.
3 of quinoline sulfonated get 8 – quinoline sulfonic acid groups, and then after alkali fusion get 8 – hydroxy quinoline bases, and finally by acidification to give 8 – hydroxy quinoline. Preparation process is as follows:
① sulfonation quinoline as raw materials in the raw material was added slowly with stirring to sulfuric acid in a sand bath heated at 100 ~ 180 ℃, sulfonated 2 ~ 3h. Then cooled to room temperature, then further cooled ice, filtered dried to give product 8 – quinoline sulfonic acid.
② alkali melt process under stirring, the sulfonated product was added slowly to the molten base, in the melt of about 200 ~ 240 ℃ 30 ~ 40min, cooled water was added and heated to dissolve all the cooling to room temperature After acid and then neutralized to pH = 7, upon crystallization, filtration, the filter cake was dry.
③ The alkali fusion product distillation process using steam distillation, cooling and crystallization is the product 8 – hydroxy quinoline.
11 The main purpose
1, is widely used for the determination and separation of metals. Precipitating agent and precipitation and separation of metal ions in the extraction agent, with the following metal ions: Cu +2, Be +2, Mg +2, Ca +2, Sr +2, Ba +2,?????? Zn? +2, Cd? +2, Al? +3, Ga? +3, In? +3, Tl? +3, Yt? +3, La +3, Pb? +2, B? +3, Sb ? +3, Cr? +3, MoO? +22, Mn? +2, Fe? +3, Co? +2, Ni? +2, Pd? +2, Ce? +3
1 used as pharmaceutical intermediates, synthetic grams Xie Li Ning, clioquinol, flutter respite sensitive materials, but also dye, pesticide intermediates. The product is a halogenated quinoline class of anti-amoebic drug intermediates, including quinoline iodoform, clioquinol, iodoquinol so on. These drugs inhibit the intestinal commensal bacteria play a role in anti-amoebic of amoebic dysentery effective, no outside influence on intestinal amoeba. Foreign reports this class of drugs can cause subacute optic neuropathy, the drug has been disabled in Japan and the United States, caused by the disease iodoquinol than clioquinol rare. 8 – hydroxy quinoline also dye, pesticide intermediates. Copper sulfate and is an excellent antiseptic, disinfectant and fungicide. The product is a complex indicator for chemical analysis.
2 is used as a complexing agent and an extractant precipitation and separation of metal ions, with Cu +2, Be +2, Mg +2, Ca +2, Sr +2, Ba +2, Zn? +2, Cd + 2, Al +3, Ga +3, In +3, Tl +3, Yt +3, La +3, Pb +2, B +3, Sb? +3, Cr +3, MoO? +22, Mn + 2, Fe +3, Co +2, Ni +2, Pd +2, Ce +3, and other metal ions. Determination of organic trace analysis of nitrogen heterocyclic organic synthesis. Also dyes, pesticides and halogenated quinoline class of anti-amoebic drug intermediates. Copper sulfate and is an excellent antiseptic .
3 of epoxy adhesive can be added to improve the metal (especially stainless steel) adhesive strength and heat aging resistance, the amount is generally 0.5 to 3 parts. Halogenated quinoline class of anti-amebic drugs intermediates, pesticide, dye intermediates. Complexometric titration can be used as an antifungal agent, a preservative and industrial polyester resin, phenol resin, and a hydrogen peroxide stabilizer, or a chemical analysis indicator .
(4) The product is an intermediate halogenated quinoline drugs, but also dyes, pesticide intermediates. Copper sulfate and is an excellent antiseptic, disinfectant and fungicide. Cosmetics maximum allowable content (mass fraction) was 0.3%, sunscreen products and products for children under 3 years of age (as talcum powder) is disabled and should indicate on the product label “disabled children under 3 years of age.” In dealing with bacterial infections and bacterial infections of the skin, eczema, lotion 8 – hydroxy quinoline mass fraction of 0.001% to 0.02%. It is also used as a disinfectant, antiseptic and fungicide, and its strong anti-fungal effect. 8 – hydroxyquinoline sulfate used in skin creams and lotions content (mass fraction) of 0.05% to 0.5%.
12 Risk Phrases
R22 Harmful if swallowed.
R37 Irritating to respiratory system.
R38 irritating to the skin. [2]
13 storage transport
Dark dry and ventilated place
14 Hazard statement
Dangerous code: Xn
Dangerous Level: 22
Povidone iodine
LUBON INDUSTRY Co., LTD are specialize in producing Povidone iodine for several years this products sell well both at home and abroad.
Povidone iodine antiseptic solution is to disinfect for suppurative dermatitis, fungal skin infections, minor burns small area, but also for a small area of skin, mucous membrane wound disinfection. Its mechanism of action is the product after contact with the wound or lesion, can release the iodine depolymerization play a bactericidal effect. Organization is characterized by irritation, applied to the skin, mucous membrane infections.
Povidone iodine Is a novel and efficient disinfectant antiseptic agents, 0.7% to 10% solution in water to release the 1.8 ~ 24 ppm free iodine, from the latter by oxidation kill microorganisms, preferably bacteria killing effect at Xianbi Tai, and has some lethal bacterial spores.
2 Povidone iodine.in the solvent gradually release iodine, play the role of a sustained release, in order to maintain a longer sterilizing time. Mechanism of its strong sterilizing pathogens puree oxidation activity of the protein group, and capable of binding to denatured protein and amino group, thereby effectively kill bacteria, spores, fungi, protozoa, viruses and other pathogens. Has a strong bactericidal bactericidal wide range of stimulating small, stained yellow light, easy to clean, no allergic reactions, etc.
3. Povidone iodine against Staphylococcus aureus , Escherichia coli, Pseudomonas aeruginosa, Neisseria gonorrhoeae , Candida albicans and other hundreds of species of bacteria, viruses and other rapid killing effect. The product is the preferred disinfectant antiseptic drugs currently used for domestic and foreign direct human skin, mucous membranes.
4. Povidone iodine also can broad spectrum bactericidal, fungicidal and strong, can directly kill bacteria, fungi, viruses, spores and protozoa. Sterilization speed, most bacteria can kill within 30 seconds, five minutes is sufficient for an individual to kill bacteria. No stimulation of the skin and mucous membranes , can be used to disinfect and treat the body cavity, mucosa and ulcers. Non-toxic . Difficult to make microbes resistant, easy to allergic reactions . Use durable, good stability, long storage period. Soluble in water, easy to clean, no pollution or damage to the fabric and other items .
If you want to know more information or to buy this product please click our website http://www.lubonchem.com/ and contact us:
Email: sales6@lubonchem.com
Tel: 86-25-87775610,86695610
Fax : 86-25-81991787
Use of 8-Hydroxyquinoline
LUBON INDUSTRY Co., LTD is one of the largest manufacturers of 8-Hydroxyquinoline production. 8-Hydroxyquinoline is widely used. Use of 8-Hydroxyquinoline in pharmaceutical intermediates, synthetic grams Xie Li Ning, clioquinol, flutter respite sensitive materials, but also the dye, pesticide intermediates. The product is a halogenated quinoline class of anti-amoebic drug intermediates, including quinoline iodoform, clioquinol, iodoquinol so on. These drugs inhibit the intestinal commensal bacteria play a role in anti-amoebic of amoebic dysentery effective, no outside influence on intestinal amoeba. In recent years, foreign reports this class of drugs can cause subacute optic neuropathy, the drug has been disabled in Japan and the United States, caused by the disease iodoquinol than clioquinol rare. 8 – hydroxy quinoline also dye, pesticide intermediates. Copper sulfate and is an excellent antiseptic, disinfectant and fungicide. The product is a complex indicator for chemical analysis. Use of 8-Hydroxyquinoline in precipitation and separation of metal complexing agent and the ion extraction, with Cu +2, Be +2, Mg +2, Ca +2, Sr +2, Ba +2, Zn? +2, Cd +2, Al +3, Ga +3, In +3, Tl +3, Yt +3, La +3, Pb +2, B +3, Sb? +3, Cr +3, MoO? +22, Mn +2, Fe +3, Co +2, Ni +2, Pd +2, Ce +3, and other metal ions. Determination of organic trace analysis of nitrogen heterocyclic organic synthesis. Also dyes, pesticides and halogenated quinoline class of anti-amoebic drug intermediates. Copper sulfate and is an excellent preservative. Epoxy adhesive can be added to improve the metal (preferably stainless steel) of the adhesive strength and heat aging resistance, the amount is generally 0.5 to 3 parts. Halogenated quinoline class of anti-amebic drugs intermediates, pesticide, dye intermediates. Complexometric titration indicator can be used as fungicides, preservatives and industrial polyester resins, phenolic resins and hydrogen peroxide stabilizers, or chemical analysis. (4) 8-Hydroxyquinoline is an intermediate halogenated quinoline drugs, but also dyes, pesticide intermediates. Copper sulfate and is an excellent antiseptic, disinfectant and fungicide. Cosmetics maximum allowable content (mass fraction) was 0.3%, sunscreen products and products for children under 3 years of age (as talcum powder) is disabled and should indicate on the product label “disabled children under 3 years of age.” In dealing with bacterial infections and bacterial infections of the skin, eczema, lotion 8 – hydroxy quinoline mass fraction of 0.001% to 0.02%. It is also used as a disinfectant, antiseptic and fungicide, and its strong anti-fungal effect. 8 – hydroxyquinoline sulfate used in skin creams and lotions content (mass fraction) of 0.05% to 0.5%. If you want to know more information or to buy this product please click our website http://www.lubonchem.com and contact us: Email: sales6@lubonchem.com Tel: 86-25-87775610, 86695610 Fax : 86-25-81991787.
Minoxidil pilatory
Originally, the function of minoxidil is control high blood pressure, later, it was discovered that there is an interesting side effect is to reverse or slow down the balding process. Upjohn introduced a 2% minoxidil topical liquid, used to treat baldness and hair loss.
Next let us learn about Minoxidil pilatory function in the pharmacodynamic. Minoxidil pilatory function in Minoxidil (a) to stimulate follicular epithelial cell proliferation .Minoxidil Sulfate all have their role in hair growth. In vitro experiments showed that the role of minoxidil sulfate is 14 times minoxidil, if added sulfotransferase inhibitors or sulfuric acid scavengers, inhibit hair growth effects of minoxidil pilatory , but the sulfuric acid metabolite the role of no effect. Animal experiments have shown: Minoxidil pilatory can increase the dermal papilla, hair matrix, the number of fibroblasts synthetic outer root sheath and hair around, thus prolonging the hair long, and promote a hair to terminal hair transformation.
Minoxidil pilatory used for opening potassium channels: potassium channel opening is an important step in regulating hair growth in vitro and in vivo experimental animal models have shown that minoxidil pilatory is a potassium channel activator, can increase the potassium ion permeability to prevent the inflow of calcium ions within the cell when, resulting in cell free calcium concentration decreased, while calcium ions, epidermal growth factor inhibiting hair growth.
If you want to learn more about the minoxidil pilatory, pls click here, http://www.lubonchem.com/products_all.html?page=5&disp_order=1 . Lubon Industry Co., Ltd will provide the most comprehensive information, the most reasonable price and the best quality service for you! If you have any questions, pls contact us without hesitation through these ways:
Pls contact us:
Sales4:Ms. Joan Ye
Email: sales4@lubonchem.com
Tel: 86-25-87775610, 86695610
Fax: 86-25-81991787
praziquantel
LUBON INDUSTRY CO.,LTD. as a professional chemical manufacturer , we can be confident to tell you we can provide the high quality praziquantel with you and the price can be best.It has many other names such as drontal,drontal plus,Vercom; 2(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one;4H-Pyrazino(2,1-a)isoquinolin-4-one;2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-;biltricide;pyquiton.
praziquantel‘s chemical properties can perfect as white or white crystalline powder . In addition to know about the chemical property of praziquantel , most important of all, we should understand it playes a powerful role in pharmacological effects.For example,praziquantel as a broad spectrum trematode and tapeworm drug resistance, it is suitable for all kinds of schistosomiasis, clonorchiosis, paragonimiasis, Jiang Pianchong disease ,taeniasis and cysticercosis.
Not only that, praziquantel as a broad-spectrum parasite drug resistance has been widely used in medicine. It has been made the new preparations such as liposomes, micro capsule and so on .On the one hand, praziquantel can increase it’s curative effect and use, to reduce the side effects. On the other hand,studying on the new dosage forms can overcome the first effect, low bioavailability, short half-life and other defects.
In a word, if you want to have further information about praziquantel.pls don’t hesitate to contact us.